Current Research

Periodontal regeneration & Periodontal tissue engineering.

Background

B.D.S. March 1994 (Tsurumi University).

D.D.S and Ph. D. March 2000 (Tsurumi University).

Periodontal surgery and periodontal plastic surgery training at Tsurumi University between 1996-2004.

Awards and Scholarships

• Best article award of Tsurumi University Dental Journal, Thesis: “Periodontal regeneration activity of protein fractions obtained from the enamel matrix derivatives by the ammonium sulfate fraction”

Supervisors: Prof. Takashi Arai, Prof. Makoto Fukae, Associate Prof. Kazuhiro Gomi

Publications

K. Gomi, S. Saitoh, M. Kanazashi, T. Arai, J. Nakamura, “The effects of surface roughness of titanium plate on the behavior of osteoclast-like cells,” J Jpn Soc Oral Implant, vol. 9, pp. 74-80, 1996. (Japanese)

K. Gomi, S. Kobayashi, M. Nakano, H. Yamaguchi, M. Kanazashi, M. Kobuna, T. Arai, J. Nakamura, “The effects of Er- and Nd YAG Laser surface on disinfection for infected root canals,” Jpn J Conserv Dent, vol. 40, pp. 800-806, 1997. (Japanese)

K. Gomi, S. Kobayashi, M. Kobuna, M. Kanazashi, M. Hirai, T. Arai, “Heterotopic bone formation in subcutaneous sites of rats using hybrid materials compounded with hydroxyapatite and osteogenic cells,” J Jpn Soc Periodontol, vol. 39, pp. 503-512, 1997. (Japanese)

M. Arase, J. Yamamoto, K. Fujita, S. Saitoh, M. Kanazashi, H. Yamaguchi, I. Watanabe, T. Watanabe, T. Arai, “A survey of periodontal disease using CPITN in research institute of electric corporation,” Jpn J Conserv Dent, vol. 42, pp. 520-528, 1999. (Japanese)

M. Kanazashi, K. Komatsu, “In vitro effects of EDTA and pH on biomechanical properties and morphological features of the rat molar periodontal ligament,” J Oromax Biomech, vol. 5, pp.1-16, 1999.

K. Gomi, M. Kanazashi, K. Enatsu, T. Yanagisawa, K. Kobayashi, N. Sugawara, T. Arai, “Effects of b-FGF on heterogenetic bone formation in hybrid materials compounded with carriers and osteogenetic cells,” J Jpn Soc Peiodontol, vol.43, pp. 52-64, 2001. (Japanese)

O. Miyashita, M. Kanazashi, T. Nagano, K. Gomi, “Histological study of mineralized tissues stimulated by enamel matrix protein,” Jpn J Conserv Dent, vol. 45, pp. 773-779, 2002. (Japanese)

K. Komatsu, M. Kanazashi, T. Arai, M. Chiba, “Effects of hydrocortisone and beta-aminopropionitrile on stress-strain and stress-relaxation behaviors, and birefringent retardation of collagen fibers in the rat incisor periodontal ligament,” Connect Tissue Res, vol. 43, pp. 581-588, 2002.

K. Komatsu, M. Kanazashi, A. Shimada, T. Shibata, A. Viidik, M. Chiba, “Effects of age on the stress-strain and stress-relaxation properties of the rat molar periodontal ligament,” Arch Oral Biol, vol. 49, pp. 817-824, 2004.

A.Suzuki, G. Ji, Y. Numabe, M. Muramatsu, K. Gomi , M. Kanazashi, Y. Ogata, E. Shimizu, Y. Shibukawa, A. Ito, T. Ito, A. Sugaya, T. Arai, S. Yamada, S. Deguchi, K. Kamoi, “Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese,” Biochem Biophys Res Commun, vol. 317, pp. 887-892, 2004.

K. Gomi, M. Kanazashi, D. Lickorish, T. Arai, J. E. Davies, “Bone marrow genesis after subcutaneous delivery of rat osteogenic cell-seeded biodegradable scaffolds into nude mice,” J Biomed Mater Res, vol. 71A, pp. 602-607, 2004.

M. Kanazashi, K. Gomi, T. Tanabe, T. Nagano, M. Fukae, T. Arai, “Periodontal regeneration activity of protein fractions obtained from the enamel matrix derivatives by the ammonium sulfate fraction,” Tsurumi Univ Dent J, vol. 33, pp. 225-230, 2004. (Japanese)

K. Gomi, A. Yashima, S. Shirakawa, M. Kanazashi, K. Kobayashi, T. Nagano, H. Yamaguchi, T. Arai, “Effects of low-level hard laser irradiation on mineralization in tree-dimensional cultured rat bone marrow cells,” J Oral Laser Applications, vol. 5, pp. 145-150, 2005.

K.Gomi, N.Shibukawa, A.Yashima, F.Iino, M.Kanazashi, T.Ohshima, N.Maeda, T.Arai, “Change of Subgingival Bacterial Flora and Drug Concentration Level in Gingiva of Periodontal Patients Systemically Administered Azithromycin,” Dentistry in Japan, vol. 41, pp. 151-155, 2005.

M. Fukae, M. Kanazashi, T. Nagano, T. Tanabe, S. Oida, K. Gomi, “Porcine Sheath Proteins Show Periodontal Ligament Regeneration Activity,” Euro J Oral Sci, in press.

M. Kanazashi, K. Gomi, T. Nagano, T. Tanabe, T. Arai, M. Fukae, “The 17kDa sheath protein in enamel proteins induces cementum regeneration in experimental cavities created in a buccal dehiscence model of dogs,” J Periodont Res, in press.

Abstracts

K. Gomi, S. Saitoh, M. Kanazashi, T. Arai, J. Nakamura, “The effects of surface roughness of titanium plate on the behavior of cells,” J Jpn Soc Peiodontol, vol. 38, October, pp. 165, 1996. (Japanese)

M. Kanazashi, N. Shibukawa, K. Gomi, T. Arai, “Application of biodegradable polymer to the dog artificial bone defects,” J Jpn Soc Peiodontol, vol. 43, October, pp. 171, 2001. (Japanese)

M. Kanazashi, K. Gomi, T. Nagano, K. Oikawa, S. Shirakawa, T. Ishio, K. Kobayashi, H. Yamaguchi, T. Arai, “The effects of enamel matrix derivatives on human dental pulp cells,” Jpn J Conserv Dent, vol. 46 AUTUMN ISSUE, pp. 86, 2003. (Japanese)

M. Kanazashi, K. Gomi, T. Tanabe, H. Yamaguchi, K. Kobayashi, T. Nagano, S. Oida, M. Fukaeand, T. Arai, “Ability of cement formation by fraction of porcine enamel protein,” J Jpn Soc Peiodontol, vol.45, April, pp. 117, 2003. (Japanese)

T. Ishio, T. Nagano, M. Kanazashi, K. Gomi, T. Arai, “The response of alkaline phosphatase positive human dental pulp cells to growth factors,” Jpn J Conserv Dent, vol. 48 SPRING ISSUE, pp. 31, 2005. (Japanese)

S. Shirakawa, T. Nagano, K. Gomi, M. Kanazashi, S. Oida, M. Fukae, T. Arai, “Effects of mechanical stress on human periodontal ligament cells,” J Jpn Soc Peiodontol, vol. 47, April, pp. 91, 2005. (Japanese)

Personal Interests

Reading about histology, baseball fan, playing with my children Yuki and Koki